MEDICINAL MYSTERIES OF IBOGA
What is Ibogaine? – A healing medicine from the rain forest, a drug used in tribal rituals, an effective addiction interrupter used in detoxification and recovery programs for patients who have tried other methods of substance abuse rehabilitation.
Ibogaine clinical studies by leading research facilities have shown that Ibogaine from the Iboga tree is an effective addiction interrupter for most chemical substances including opiods, heroin, cocaine, alcohol, methadone, methamphetamine, and even nicotine addiction.
“Ibogaine Therapy can help fight addiction where other forms of rehabilitation and intervention have failed.”
Medical studies of Ibogaine medicine reviewed before and after treatment results of cociane, alcohol and heroin addicts that had undergone ibogaine treatment at Ibogaine therapy clinics in Costa Rica, Canada, the Bahamas and Mexico.
Patients formerly addicted to heroin, cocaine, alcohol and methamphetamine shared their treatments results, effects, side effects and current perspectives about using Ibogaine treatment to break the cycle of addiction.
Ibogaine Medicine is an Addiction Disruptor used to Treat Drug and Alcohol Addiction and Alleviate Withdrawal Symptoms during Detox and Recovery.
IBOGAINE TREATMENT CONSULTATION
Contact an Ibogaine Treatment Specialist to learn more about the use of Ibogaine in a Medically Supervised Detoxification and Chemical Dependence Rehabilitation Program.
If you are looking for physician-monitored therapy and the best Ibogaine treatment clinic, contact us at 215-853-2287 for more treatment information.
“Ibogaine Therapy can help fight addiction where other forms of rehabilitation and recovery have failed.”
IBOGAINE FOR LIFE WITHOUT ADDICTION
Are you ready to change your life? We are here to support your full recovery with holistic recovery and detoxification therapies. Our professional treatment team personally tailors and closely supervises your therapeutic program.
Ibogaine therapy offers an intensive healing experience with detoxification that disrupts addiction cravings and withdrawal symptoms. Our treatment team is here for you to support your continued recovery post treatment to ensure lasting benefits.
A medical team supports your Ibogaine-assisted detoxification and recovery with a comprehensive rehab program offering therapeutic, educational and medically-supervised detoxification. Ibogaine treatment clinics are located in serene, natural habitats with a combination of Naturopathic and Integrative Medicine and on-site medical supervision. Diet, exercise, stress reduction, vitamin and restorative nutrition are key to successful, enduring recovery.
Ibogaine is a powerful indigenous plant medicine shown to be effective in the treatment of chemical dependence and alcohol addiction but it is not for everyone. Careful medical screening and health evaluation is required before a person enrolls in a treatment program.
IBOGA MEDICAL RESEARCH ARTICLE
UNIVERSITY OF LAS VEGAS Author: M. Rose
The Medical Mysteries of the Iboga Plant
Plants as medicine. Throughout time and transcending cultures humans have used plants for their healing capabilities, and thus today these plants are templates in modern medication. The use of plants is seen throughout medicine, from the commonly used aspirin derived from the willow tree, to morphine derived from the poppy plant. The scientific community is growing in modern pharmacological development, however plants remain the template in creating new medication. Yet, the world of botany is extensive and there is much more to be discovered.
The iboga plant is among one of these untapped healing resources found in nature. It has shown to have anti-drug addiction properties and the ability to combat withdrawal symptoms. Even though the iboga plant has been used for centuries by indigenous tribes, little is known about its ability for drug interruption. Thus, the iboga plant’s origin, its anti-addiction properties and neurological effects need to be analyzed to further understand the medicinal value of this mysterious plant.
In 1889, botanist Baillon scientifically classified the iboga plant with the genus Tabernanthe iboga H. Bn, and even though this may have been the first formal introduction of iboga to western science the plant has been known and used for centuries.
The iboga plant originated in central Africa growing in many areas of the western coast, but its preferred atmosphere is the highly humid and hot region of Gabon. The plant is a wild leafy shrub with bundles of small white flowers that become yellow fruit, and it can grow from five to eight feet tall. For centuries the indigenous bwiti people of Gabon have cultivated the iboga root, which when consumed in small doses can combat fatigue and heighten concentration, while large dose consumption leads to a psychotropic effect.
The exterior layer of the iboga root has many alkaloid, some still unknown, but the primary one ibogaine is responsible for the hallucinations or visions that are experience with the consumption of the root. The bwiti use the iboga root in ceremonies to evoke an inner trance along with visions that are believed to be a connection to the spiritual world. These ceremonies vary, and can be associated to the initiation of a boy into manhood, or a female initiation into a healing position within the tribe (Ravalec, Mallendi, & Paicheler, 2007). The iboga root has grown in Africa and been used by the bwiti people for centuries, however its introduction to the western world has been much more recent.
The first discovery of the iboga shrub, noted in the western culture, was by the white settlers in Gabon at the beginning of the 19th century, however the plant was not scientifically classified until eighty years later. Furthermore, it took another fifty years after classification for the iboga plant to be used medicinally.
In 1939, the Lambarene clinic, opened by the French Dr. Schweitzer, marketed the first anti-fatigue medication dervived from, a cousin of the Tabernanthe iboga root, the Tabernanthe manii root. This low dose medication widely became used by the athletic community, and was accordingly labeling as a “neuromuscular stimulant, promoting cellular combustion and eliminating fatigue; recommended in cases of depression, asthenia, convalescence, infectious disease, abnormal intellectual or physical effort in a healthy individual … rapid and sustained effect without subsequent depression” (Ravalec, 2007, p. 119-120). At this time there was no interest in the visionary aspect of the iboga root, and large does where thought to be toxic.
Eventually, in the 1950’s the iboga root made its way to the United States and the extracted alkaloid ibogaine became used in high doses. In 1955, Dr. Harris Isbell, working for the CIA, preformed experiments using ibogaine and LSD on eight heroine addicted African American prisoners. About two decades later it was revealed that Dr. Isbell’s work was the first indication of ibogaine’s anti-drug properties, unfortunately at the time this information was unknown to the public (Ravalec, 2007). During the same time, other experiments where conducted focusing on ibogaine’s psychotherapeutic properties for traumatized World War II veterans and for anti-anxiety properties. In 1962, Howard Lotsof, a heroine addict, inversely consuming ibogaine to get high, instead noticed a diminishment in cravings and lack of withdrawal. His future attributes began the research focusing on the anti-drug addiction properties of ibogaine. Even though Ibogaine is classified as a Schedule I narcotic in the United States many other countries have legalized it for use in drug interruption therapy (Donnelly, 2011).
You can find Ibogaine clinics in Europe, the Bahamas, Costa Rica, Canada, Mexico
Today, there are many ibogaine clinics around the world, and among these providers is the “I begin again” community. Lex Kogan, an ibogaine administrator for over 12 years and founder of multiple centers from Europe to Central America, is a pioneer of this ibogaine community striving to rid the world of alcohol and drug addiction. He describes ibogaine initially as a replacement therapy similar to hormone replacement therapy, regulating the body’s equilibrium state and allowing a true release without victimizing the individual’s self identification in the process (Lex Kogan, 2013).
Ibogaine affects the physical motility, visual and auditory aspects of the mind and body. During a low dose session an individual’s appetite and thirst is decrease, fatigue is reduced, and there is an increase in alertness (Donnelly, 2011); such functions are all associated to the cholinergic pathway (Ravalec, 2007).
While a high dose simulates a visual state described as a “panoramic recall of a large amount of material relating to prior life events from long-term memory,” or also know as the “waking dream state” (Donnelly, 2011, p. 98). This hallucinatory state has been associated with ibogaine’s binding to serotonin receptors (Ravalec, 2007). It is thought that this visionary state is the therapeutic element that aid recovery by allowing the individual to see where their addiction has stemmed from.
Nevertheless, to make ibogaine’s anti-withdrawal properties available to the American public, the hallucinatory effect has to be eliminated to change ibogaine’s classification from a Schedule I narcotic. The chemical 18-MC synthesized from Ibogaine, by Dr. Glick, provides all the Ibogaine anti-craving properties without the visual aspect experience by ibogaine (Donnelly, 2011). Unfortunately, as mentioned by Lex Kogan, an 18-MC patch will increase the potency of other street drugs, and most likely will lead to being abused, increasing the over-dose rate rather than aiding in drug interruption. Still today, little is known about how the full effects of Ibogaine work with association to addiction interruption, however it’s seen that ibogaine is the better alternative when compared to traditional synthesized products used in addiction recovery.
The precise neurological affects of ibogaine are still a mystery in the scientific community. Ibogaine indirectly increase extracellular serotonin neurotransmitters by non-competitively inhibiting SERT (serotonin transporters), and its chemical structure closely resembles serotonin neurotransmitter. Thus, it was believed that ibogaine bound to the substrate site of SERT, when in fact, this has been an incorrect assumption. Ibogaine bound to the outside of the cell induces serotonin transport blockage, however it has no effect when bound on the inside cytoplasmic portion of the cell. The binding of 5-HT on the inside of the cell increases serotonin transport, however high serotonin concentration on the outside of the cell will not overcome Ibogaine’s induced inhibition. Thus, the established the difference between 5-HT and ibogaine induced current on permeability of the ion pathway, illustrated ibogaine’s binding site to be different from that of the substrate binding site.
Furthermore, ibogaine similarly affects the DA transporter, even though its structure does not resemble the dopaminergic neurotransmitter (Bulling, Schicker, Zhang, Steinkellner, Stockner, Gruber, … Sandtner, 2012). Unfortunately, the knowledge of neurobiology associated with ibogaine is still changing, and presently remains a mystery.
In conclusion, there is a lot more to learn about ibogaine, and to understand the mysteries of the iboga plant one needs to analyze its origin, anti-addictive properties and neurobiology effects. The iboga root has been used for centuries by the bwiti before it was discovered and used in the western culture. The one thing that cannot be disproves is that ibogaine aids in addiction interruption. It may not be a magic pill, but it stops withdrawal symptoms and reduces cravings long enough for addicts to receive therapeutic outpatient treatment.
Lex Kogan, the leading Ibogaine Treatment pioneer, stated that approximately 70% of the 1200 addicts he’s treated have remained clean, and 100 % of the ibogaine treated traumatized victims continue to live today without post-trauma relapse. Presently, the neurological effects of the iboga root are still not well know, however the ibogaine alkaloid is similar to the serotonin chemical structure, and ibogaine is thought to work on the serotonin, acetylcholine and dopamine pathways. In the end, the scientific world has a lot to earn about the mysterious plant iboga.
Bulling, S., Schicker, K., Zhang, Y., Steinkellner, T., Stockner, T., Gruber, C.W., … Sandtner, W., (2012). The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters. J Biol Chem, 287(22): 18524–18534. doi: 10.1074/jbc.M112.343681
Donnelly, J.R., (2011). The Need for Ibogaine in Drug and Alcohol Addiction Treatment. Journal of Legal Medicine, 32(1): 93-114.
Kogan, Lex., (2013, July 5). Phone interview.
Ravalec, V., Mallendi, Paicheler, A., (2007). Iboga: The Visionary Root of African Shamanism. Rochester, Vermont: Park Street Press. (Original work published 2004).